Product Specification: Diflubenzuron 98% TC

Chemical Name: 1-(4-chlorophenyl)-3-(2,6-difluorobenzoyl)urea
Common Name: Diflubenzuron
CAS Number: 35367-38-5
Molecular Formula: C₁₄H₉ClF₂N₂O₂
Molecular Weight: 310.68 g/mol
Formulation Type: Technical Concentrate (TC)
Purity: ≥98% (by HPLC or GC)

Description:

Diflubenzuron 98% TC is a high-purity technical-grade insect growth regulator (IGR) belonging to the benzoylurea class of compounds. It is a chitin synthesis inhibitor that disrupts the development of immature stages of insects by interfering with the formation of their exoskeleton. Unlike traditional neurotoxic insecticides, Diflubenzuron affects insects by inhibiting the production of chitin, leading to death during molting.

This compound is widely used in agriculture, forestry, public health, and veterinary pest control. It is particularly effective against larval stages of Lepidoptera, Coleoptera, Diptera, and other pest species, with low toxicity to mammals, birds, and beneficial insects such as bees.

Physical and Chemical Properties:

• Appearance: White to off-white crystalline powder

• Odor: Odorless or mild odor

• Melting Point: 228–230°C

• Boiling Point: Decomposes before boiling

• Density: ~1.68 g/cm³

• Vapor Pressure: Very low (<1 × 10⁻⁷ mmHg at 25°C)

• Solubility: Slightly soluble in water (0.02 mg/L at 20°C); soluble in organic solvents such as acetone, methanol, and dimethyl sulfoxide (DMSO)

• Stability: Stable under normal conditions; hydrolytically stable at pH 5–7, but slowly degrades in alkaline conditions (pH >9)

Specification Parameters:

• Diflubenzuron Content (HPLC/GC): ≥98.0%

• Water Content (Karl Fischer): ≤0.5%

• Acidity (as H₂SO₄): ≤0.2%

• Insolubles in Acetone: ≤0.5%

• Appearance: Crystalline powder, free from visible impurities

Applications:

Diflubenzuron 98% TC is used to manufacture formulations such as:

• Wettable powder (WP)

• Suspension concentrate (SC)

• Granules (GR)

• Baits and slow-release formulations

Target Pests:

• Caterpillars (e.g., gypsy moth, armyworms, loopers)

• Beetle larvae (e.g., Colorado potato beetle, weevils)

• Fungus gnats and mosquitoes (in larval stage)

• Forest pests (e.g., pine processionary moth, spruce budworm)

Crops and Use Areas:

• Cotton, rice, vegetables, citrus, soybeans, forest trees

• Public health (mosquito larval control in water bodies)

• Mushroom houses, ornamental plants

Mode of Action:

Diflubenzuron acts by inhibiting chitin synthase enzymes, preventing the formation of chitin—a key component of the insect exoskeleton. Without chitin, immature insects are unable to molt properly, resulting in death during their development stages. The compound does not affect adult insects directly, which makes it environmentally safer and selective for pest control programs.

Toxicological Profile:

• Oral LD₅₀ (rat): >10,000 mg/kg (very low toxicity)

• Dermal LD₅₀ (rat): >2,000 mg/kg

• Inhalation LC₅₀ (rat, 4h): >2.12 mg/L

• Irritation: Non-irritating to skin and eyes (based on animal studies)

• Carcinogenicity/Mutagenicity: Not considered carcinogenic or mutagenic

• Ecotoxicology: Toxic to aquatic invertebrates; low toxicity to fish, birds, and bees

Packaging and Storage:

• Standard Packaging: 25 kg fiber drums or kraft paper bags with PE inner liner

• Storage Conditions: Store in a cool, dry, and well-ventilated area; protect from moisture and direct sunlight

• Shelf Life: Minimum 2 years in original, unopened packaging under recommended conditions

Safety and Handling:

Use personal protective equipment during handling. Avoid inhalation and contact with skin or eyes. Follow local regulations for transportation, formulation, and disposal. Refer to the SDS for detailed safety information.

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